Cancer screenings in the U.S. - Mean weekly screening volume for breast, colon, and cervical cancer
Briefs • 

EHR data show a recent abrupt drop – between 86% and 94% – in preventive cancer screenings performed across the United States, presumably due to access disruptions caused by COVID-19. This study compares the number of screenings for cervical, colon, and breast cancer completed each week in 2020 to the average number of screenings completed…

Ochsner in Louisiana
Research UpdatesOchsner Health System • 

Researchers from Ochsner and local lab BioInfoExperts have sequenced the genetic code of samples from their COVID-19 patients to learn more about the virus’s spread in Louisiana and how it continues to evolve. New Orleans has not only some of the highest per-capita rates of COVID-19 infection, but also a high rate of underlying health…

Prior Outpatient Medications and Subsequent COVID-19 Positive Status
Briefs • 

As the COVID-19 pandemic sweeps the globe, there is a rush to find medications that, if taken before COVID-19 is acquired, may be protective against infection. Clinical trials are currently examining drugs in many different classes including antimalarials, antivirals, angiotensin converting enzyme inhibitors, angiotensin receptor blockers, interleukin inhibitors, and more.1 Figure 1 shows the percentage…

Ventilator survival by age and sex
Briefs • 

Here we examine the mortality of patients who received invasive mechanical ventilation as treatment for acute respiratory failure due to COVID-19.  As of April 30, 2020, for COVID-19 positive patients age 19+ requiring invasive mechanical ventilation (n = 8650), 1833 (21%) were discharged from the hospital, 3847 (44%) died, and 2970 (34%) remain in the…

Cleveland Clinic Miller Family Pavillion
Eric Boose, MD • Christopher Babiuch, MD • Michelle Medina, MD • Adrienne Boissy, MD • Matthew Kull • Amy Merlino, MD
InnovatorsCleveland Clinic • 

Story contributed by Cleveland Clinic. Never before has the need to leverage technology for population health management been more apparent. With the outbreak of COVID-19, consistent outreach and prompt intervention are necessary to prevent negative outcomes. Although patients with COVID-19 often experience mild symptoms, deterioration can be rapid, even in patients considered low risk. That’s…

Genome sequencing holds clues about the progression of COVID-19 in New York City and offers hints about where to look next.
Research UpdatesNYU Langone Health • 

Researchers at NYU Langone have sequenced the genetic code of samples from 91 COVID-19 patients in New York City, seeking clues to its origin and evolution in this region. Early data suggest that the virus has been spreading in the city for two months, before testing started. The findings also indicate the New York City…

COVID-19 testing rates by age and sex, compared to the overall population
Briefs • 

Investigators examined which patient populations are most likely to be tested for COVID-19, test positive for COVID-19, and have the most severe outcomes. The analysis below includes 165,359 patients tested for COVID-19 and 66,017 COVID-19 positive patients as of April 17, 2020. Data are pooled from 22 health systems that represent 140 hospitals, spanning 11…

Worst severity probability by prior ibuprofen prescription by age and sex
Briefs • 

Investigators examined whether patients who were prescribed ibuprofen before they were infected with COVID-19 showed a difference in disease severity. Patients who were prescribed ibuprofen before infection had less severe outcomes. This appeared to be the case regardless of sex or age group. We include patients in the “prescribed ibuprofen” group if they had a…